Reset Ketamine September 17, 2018 Alternative Therapies, Ketamine, Psychedelic, Support, Experience, Beginners Guide Set and Setting During Ketamine Infusions Reset Ketamine September 17, 2018 Alternative Therapies, Ketamine, Psychedelic, Support, Experience, Beginners Guide There are two important factors to consider when undergoing your ketamine infusions. These are the patient’s mindset (set) and the environment (setting) where the infusion will occur.