This is a transcript of the video which has been edited for readability.

When it is time for your first ketamine infusion, you need to be aware that there are some medications that can decrease the effectiveness of ketamine. Additionally, there are medications that also interact with ketamine. We’ll reveal all of these medications in today’s blog post.

There are a few medications that could affect the effectiveness of ketamine. Do speak with your ketamine specialist first to seek proper advice.

Medications That Decrease Ketamine’s Effectiveness

The two most commonly observed medications that could decrease the effectiveness of ketamine are lamotrigine and another category of medications called benzodiazepines. Multiple studies have shown that when someone is taking either of those medicines or even both, it could reduce the effectiveness as well as the duration of the ketamine experience and effectiveness.

Medications That Interact with Ketamine

What's interesting is there's a few other medications that could also interact with ketamine. Those medications are clozapine, haloperidol and risperidone. There needs to be more research on the interaction of ketamine with those three medications, but there definitely seems to be some interactions between those.

Conversely, we've had patients who are on SSRIs and SNRIs but don’t experience significant interaction from the ketamine. This means someone can be taking some antidepressants and still get the maximal effect from ketamine.

Your Ketamine Specialist Knows Best

This was a quick look at the medications that may not work well with your ketamine treatment. Do note that what's really important is that you speak with your ketamine specialist so that they can review which medications may or may not be helping you during your ketamine experience. Always remember, never change how much medications you are taking or stopping medications without the supervision of your doctor.